Contents:
1.
Druggable Signaling Proteins 2.
DNA Methylation and Histone Modifications
in Patients With Cancer: Potential Prognostic and Therapeutic targets 3.
Wnt Signaling as a Therapeutic
Target for Cancer 4.
The NG2/HMP Proteoglycan as a Cancer
Therapeutic Target 5.
Heterotrimeric G Proteins and Disease 6.
High-Mobility Group Box-1 Isoforms
as Potential Therapeutic Targets in Sepsis 7.
Antisense Oligonucleotides:
Target Validation and Development of Systematically Delivered Therapeutic
Nanoparticles 8.
Nucleic Acid-Based Aptamers as
Promising Therapeutics in Neoplastic Diseases 9.
Guidelines for the Selection of
Effective Short-Interfering RNA Sequences for Functional Genomics 10. Suppression
of Apoptosis in the Liver by Systemic and Local Delivery of Small-Interfering
RNA 11. Target
Validation Using RNA Interference in Solid Tumors 12. Validation
of Telomerase and Survivin as Anticancer Therapeutic Targets Using Ribozymes
and Small-Interfering RNAs 13. Collagen-Induced
Arthritis in Mice: A Major Role for Tumor Necrosis factor-a 14. Novel
Opportunities for Therapeutic Targeting in Systemic Autoimmune Diseases 15. Considerations
for Target Validation and Industrial Approaches 16. Regulatory
RNAs: Future Perspectives in Diagnosis, Prognosis, and Individualized
Therapy 17. Treatment Options and Individualized Medicine
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