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Book Details
Pharmacokinetic Analysis: A Practical Approach
Author(s) :Lee Peter I.D., Gordon L.Amidon
ISBN
:
9781566764254
Name
:
Pharmacokinetic Analysis: A Practical Approach
Price
:
1395.00
Author/s
:
Lee Peter I.D., Gordon L.Amidon
Type
:
Text Book
Pages
:
548
Year of Publication
:
Rpt.2011
Publisher
:
Taylor & Francis/BSP Books
Binding
:
Paperback
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Contents:
SECTION I: Basics and methods
1.
Introduction,
2.
Time Constant Approach,
3.
Evaluation of Time Constants by Visual Inspection of Concentration- Time Profiles,
4.
Scaling of Time Constants among Different Animal Species,
SECTION II:
Formulation factors
5.
Influence of
Administration Route
on Pharmacokinetics- Bioavailability,
6.
Influence of Formulation on Pharmacokinetics- Bioequivalence,
7.
Influence of Dosage on Pharmacokinetics- Dose Proportionality,
8.
Pharmacokinetics of Sustained Release and Immediate Release Formulations,
SECTION III:
Absorption, Distribution, Metabolism, and Pharmacodynamics
9.
Absorption of Drugs in the Gastrointestinal Tract,
10.
Drug Distribution into Tissue- Tissue Penetration,
11.
Pharmacokinetics of Metabolites,
12.
Relationship between Pharmacokinetics and Pharmacodynamics,
SECTION IV:
Interactions
13.
Influence of Food on Pharmacokinetics,
14.
Effects of Drug Interactions on Pharmacokinetics,
SECTION V:
Special populations
15.
Influence of Age on Pharmacokinetics,
16.
Difference in Pharmacokinetics between Genders,
17.
Special Pharmacokinetic Considerations in Renal Impairment,
18.
Special Pharmacokinetic Considerations in Hepatic Impairment,
19.
Special Pharmacokinetic Considerations in Other Diseases
20.
Absorption of Drugs in the Gastrointestinal Tract.
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